Jak Knowles
Chief Executive Officer chez Affini-T Therapeutics, Inc.
Profil
Jak Knowles is the founder of Affini-T Therapeutics, Inc. (founded in 2021), and currently holds positions as Director at Vesigen, Inc. (since 2020), Vice President-Medical & Scientific Affairs at CureDuchenne, and Venture Advisor at Agent Capital LLC.
Dr. Knowles has held former positions as Chief Executive Officer & Director at CytoSen Therapeutics, Inc., Director at NewLeaf Symbiotics, Inc. (2018-2020), Director at CoverCress, Inc., Director at MyoTherix, Inc., Managing Director at CureDuchenne Ventures LLC (2015-2017), Director at Triumvira Immunologics, Inc. (2020), Director at Century Therapeutics, Inc. (2019-2020), Director at Pyxis Oncology, Inc. (2019-2020), Vice President at Bayer AG (2018-2020), Equities Analyst at JMP Securities LLC (2013), Equities Analyst at Burrill LLC, Associate at MPM BioImpact, Inc., and Principal at Oliver, Wyman & Co. LLC.
Dr. Knowles also served as an Advisory at Bamboo Therapeutics, Inc. (2015-2016), President at Exonics Therapeutics, Inc., and Board Member at RASRx LLC (2016-2017) and Trinds LLC (2016-2017).
Dr. Knowles received a doctorate degree from Stanford University in 2008 and an undergraduate degree from the State University of New York at Binghamton in 2001.
Postes actifs de Jak Knowles
| Sociétés | Poste | Début |
|---|---|---|
CureDuchenne
 CureDuchenne Financial ConglomeratesFinance CureDuchenne provides funding for research projects and organizations. The company was founded in 2003 by Paul Miller and Debra Miller and is located in Newport Beach, CA. | Corporate Officer/Principal | - |
Vesigen, Inc.
 Vesigen, Inc. BiotechnologyHealth Technology Vesigen, Inc. develops groundbreaking therapeutic products directed to intracellular targets using a scalable and extracellular vesicle delivery technology. The company is headquartered in Cambridge, MA. | Director/Board Member | 22/07/2020 |
Affini-T Therapeutics, Inc.
 Affini-T Therapeutics, Inc. BiotechnologyHealth Technology Affini-T Therapeutics, Inc. is a biotechnology company based in Watertown, MA. Affini-t is focused on developing potentially curative therapies for solid tumor cancers by unlocking the power of T cells and targeting core oncogenic drivers. The company's differentiated cell therapy platform harnesses state-of-the-art engineering and synthetic biology capabilities to optimize T cell functions and rewrite the rules of the solid tumor microenvironment, enabling the potential for sustained clinical outcomes in patients. The company is targeting Kras and other oncogenic and viral driver mutations to open a new and differentiated target space, thereby minimizing the risk of cancer. The company was founded by Jak Knowles and Arjun Goyal, with Jak Knowles serving as the CEO since incorporation. | Chief Executive Officer | 01/02/2021 |
Agent Capital LLC
 Agent Capital LLC Investment ManagersFinance Agent Capital LLC (Agent Capital) is a venture capital firm founded in 2017 by Geeta Vemuri. The firm is headquartered in Waltham, Massachusetts. | Consultant / Advisor | - |
Anciens postes connus de Jak Knowles
| Sociétés | Poste | Fin |
|---|---|---|
| METAGENOMI, INC. | Director/Board Member | 01/12/2021 |
Triumvira Immunologics, Inc.
 Triumvira Immunologics, Inc. Pharmaceuticals: MajorHealth Technology Triumvira Immunologics, Inc. develops and manufactures pharmaceutical products. The company was founded by Jonathan Bramson in 2015 and is headquartered in Hamilton, Canada. | Director/Board Member | 01/11/2020 |
| CENTURY THERAPEUTICS, INC. | Director/Board Member | 01/11/2020 |
| PYXIS ONCOLOGY, INC. | Director/Board Member | 01/11/2020 |
| BAYER AG | Corporate Officer/Principal | 01/10/2020 |
Formation de Jak Knowles
| Stanford University | Doctorate Degree |
| State University of New York at Binghamton | Undergraduate Degree |
Expériences
Fonctions occupées
Relations
Relations au 1er degré
Entreprises liées au 1er degré
Homme
Femme
Administrateurs
Exécutifs
Sociétés liées
| Sociétés cotées | 4 |
|---|---|
| BAYER AG | Health Technology |
| CENTURY THERAPEUTICS, INC. | Health Technology |
| PYXIS ONCOLOGY, INC. | Health Technology |
| METAGENOMI, INC. | Health Technology |
| Entreprise privées | 18 |
|---|---|
JMP Securities LLC
 JMP Securities LLC Investment Banks/BrokersFinance Citizens JMP Securities LLC (Citizens JMP) is a full-service investment bank and broker/dealer headquartered in San Francisco, California. The firm was founded by Joseph Jolson in 2002 and was formerly JMP Securities LLC. The firm is a subsidiary of JMP Holding LLC, ultimately held by Citizens Financial Group, Inc. (NYSE: CFG). Citizens JMP provides equity research, institutional brokerage, and investment banking services to public and private growth companies and their investors. They are a research-driven, growth-oriented firm that provides services to small- and mid-sized companies and the institutions that invest in them. The firm specializes in four high-growth sectors of the economy: technology, healthcare, financial services, and real estate. | Finance |
NewLeaf Symbiotics, Inc.
 NewLeaf Symbiotics, Inc. Chemicals: AgriculturalProcess Industries NewLeaf Symbiotics, Inc. develops and commercializes a family of beneficial bacteria. It commercializes Pink Pigmented Facultative Methylotrophs bacteria that improves plant health, promote early growth, and increase crop yield. The company was founded by Stephen Kahn, Thomas R. Laurita and Michael Bielski in 2012 and is headquartered in St. Louis, MO. | Process Industries |
Burrill LLC
 Burrill LLC Investment ManagersFinance Burril LLC (Burrill) is a private equity/venture capital firm founded in 1994 by G. Steven. The firm is headquartered in San Francisco, California. | Finance |
MPM BioImpact, Inc
 MPM BioImpact, Inc Investment ManagersFinance MPM Bioimpact Inc (MPM Capital) is a venture capital firm founded in 1996 by Ansbert K. Gadicke and Luke B. Evnin. The firm is headquartered in Boston, Massachusetts. | Finance |
CureDuchenne
CureDuchenne Financial ConglomeratesFinance CureDuchenne provides funding for research projects and organizations. The company was founded in 2003 by Paul Miller and Debra Miller and is located in Newport Beach, CA. | Finance |
| Oliver, Wyman & Co. LLC | |
CoverCress, Inc.
 CoverCress, Inc. Information Technology ServicesTechnology Services CoverCress, Inc. operates as a renewable fuel company. It develops and commercializes field pennycress as an oilseed crop that is used to produces oil for industrial and renewable fuels, and meal for nutritious livestock feed. The company was founded by Vijay Chauhan, Dennis M. Plummer and Mike Roth and is headquartered in St. Louis, MO. | Technology Services |
MyoTherix, Inc.
 MyoTherix, Inc. Pharmaceuticals: MajorHealth Technology Myotherix, Inc. operates as a biopharmaceutical company focuses on the development of therapies. It focuses on the development of innovative therapies for patients suffering from Duchenne muscular dystrophy and other muscle disorders for which there are no treatments. The company was founded by John Kincaid and is headquartered in Emeryville, CA. | Health Technology |
Bamboo Therapeutics, Inc.
 Bamboo Therapeutics, Inc. BiotechnologyHealth Technology Bamboo Therapeutics, Inc. develops gene therapy products for central nervous system and neuromuscular diseases. Its therapeutic platform is based on the use of Adeno-associated virus as a gene therapy vehicle. The company’s proprietary technologies include chimeric vectors, self-complementary vectors, and dual glycan receptor. It focuses on the treatment of Duchenne muscular dystrophy, giant axonal neuropathy, Friedreich ataxia, and Canavan disease. Bamboo Therapeutics was founded by Richard Jude Samulski, Sheila A. Mikhail, Josh Grieger, Xiao Xiao, and Paola Leone in December 2014 and is headquartered in Chapel Hill, NC. | Health Technology |
CureDuchenne Ventures LLC
 CureDuchenne Ventures LLC Investment ManagersFinance CureDuchenne Ventures LLC (CureDuchenne Ventures) is a venture capital subsidiary of CureDuchenne, founded in 2014 by Debra Miller. The firm is headquartered in Newport Beach, California. | Finance |
Triumvira Immunologics, Inc.
Triumvira Immunologics, Inc. Pharmaceuticals: MajorHealth Technology Triumvira Immunologics, Inc. develops and manufactures pharmaceutical products. The company was founded by Jonathan Bramson in 2015 and is headquartered in Hamilton, Canada. | Health Technology |
CytoSen Therapeutics, Inc.
 CytoSen Therapeutics, Inc. Miscellaneous Commercial ServicesCommercial Services CytoSen Therapeutics, Inc. develops natural killer (NK) cell therapeutics for cancer. It offers nanoparticle processing technology which enables improved ex vivo expansion and activation of NK-cells supporting multiple high dose infusions with anti-cancer cytotoxicity. The company was founded by Stefan O. Ciurea, Dean Lee and Robert Igarashi and is headquartered in Orlando, FL. | Commercial Services |
Agent Capital LLC
Agent Capital LLC Investment ManagersFinance Agent Capital LLC (Agent Capital) is a venture capital firm founded in 2017 by Geeta Vemuri. The firm is headquartered in Waltham, Massachusetts. | Finance |
Exonics Therapeutics, Inc.
 Exonics Therapeutics, Inc. BiotechnologyHealth Technology Exonics Therapeutics, Inc. develops therapies for neuromuscular diseases. It also develops gene editing technologies like CRISPR/Cas9 to permanently correct the majority of duchenne muscular dystrophy mutations. The company was founded by Eric N. Olson in February 2017 and is headquartered in Cambridge, MA. | Health Technology |
RASRx LLC
 RASRx LLC Miscellaneous Commercial ServicesCommercial Services RASRx LLC provides research and development laboratories services. The company is headquartered in San Luis Obispo, CA. | Commercial Services |
Trinds LLC
 Trinds LLC Miscellaneous Commercial ServicesCommercial Services Trinds LLC operates as a contract research organization which conducts research in neuromuscular and rare disorders. It offers solutions in clinical operations, data management, patient science liaison services, study measurements, and biostatistics. The company was founded by Avital Cnaan, Heather Gordish-Dressman and Eric Hoffman and is headquartered in Pittsburgh, PA. | Commercial Services |
Vesigen, Inc.
Vesigen, Inc. BiotechnologyHealth Technology Vesigen, Inc. develops groundbreaking therapeutic products directed to intracellular targets using a scalable and extracellular vesicle delivery technology. The company is headquartered in Cambridge, MA. | Health Technology |
Affini-T Therapeutics, Inc.
Affini-T Therapeutics, Inc. BiotechnologyHealth Technology Affini-T Therapeutics, Inc. is a biotechnology company based in Watertown, MA. Affini-t is focused on developing potentially curative therapies for solid tumor cancers by unlocking the power of T cells and targeting core oncogenic drivers. The company's differentiated cell therapy platform harnesses state-of-the-art engineering and synthetic biology capabilities to optimize T cell functions and rewrite the rules of the solid tumor microenvironment, enabling the potential for sustained clinical outcomes in patients. The company is targeting Kras and other oncogenic and viral driver mutations to open a new and differentiated target space, thereby minimizing the risk of cancer. The company was founded by Jak Knowles and Arjun Goyal, with Jak Knowles serving as the CEO since incorporation. | Health Technology |
