Arnold I. Caplan

Sapphire Therapeutics, Inc. develops biopharmaceutical products. It develops compounds for the treatment of oncologic and metabolic diseases. The firm products include anamorelin for the treatment of anorexia and cachexia. The company was founded in 2000 and is headquartered in Bridgewater, NJ.

TYRX, Inc. designs and manufactures medical-pharmaceutical combination devices. The firm commercializes implantable combination drug and device products focused on infection control including the AIGISRx Antibacterial Envelope, designed to reduce surgical site infections associated with cardiac implantable electronic devices (CIEDs). Its AIGISRx products contain the antimicrobial agents, rifampin and minocycline, which have been shown to reduce infection by pathogens responsible for the majority of CIED infections, including superbugs such as methicillin-resistant S. aureus (MRSA). The company was founded in 1998 by Satish Pulapura and Arikha Moses and is headquartered in Monmouth Junction, NJ.

Shire Regenerative Medicine, Inc. develops and commercializes living cell therapies. It manufactures and markets dermagraft, a bio-engineered skin substitute that assists in restoring damaged tissue and supports the body's natural healing process. The company was founded in 2004 and is headquartered in Westport, CT.

Lux Biosciences, Inc. provides therapies for treatment of ophthalmic diseases. It develops and commercializes medications for ophthalmic diseases. The company was founded by Ulrich M. Grau, Eddy Anglade, Clarke A. Atwell and Sidney L. Weiss in 2006 and is headquartered in Jersey City, NJ.

BioRez, Inc. engages in the design and development of resorbable polymer scaffold technology. The firm offers a device that is suited for tendon, ligament, and other soft tissue injuries. The company was founded by Cato T. Laurencin and Joseph W. Reilly in 2008 and is headquartered in New Haven, CT.

Hapten Sciences, Inc. is a biopharmaceutical company. It identifies and develops novel, early-stage products that contribute to the health and well being of people around the world. Its product include PDC-APB, a small molecule that acts like a vaccine to prevent the extremely painful itching and rash. The company was founded by Raymond Joseph Hage Jr. and is headquartered in Memphis, TN.

Crossroads Extremity Systems LLC provides orthopedic foot and ankle fixation services. It also offers fusion system, stropp plantar plate, nitinol clips, bone screws, and allograft and wedges products. The company was founded in 2013 and is headquartered in Memphis, TN.

Burril LLC (Burrill) is a private equity/venture capital firm founded in 1994 by G. Steven. The firm is headquartered in San Francisco, California.

University of Washington functions as a College/University. The company is headquartered in Seattle, WA.

Novo Nordisk Fonden provides basis for the commercial and research activities conducted by the companies. It also supports scientific and humanitarian purposes activities. It awards grants for research within biomedicine, biotechnology, general practice and family medicine, nursing, and art history at public research institutions. It bridges gap between the discoveries made by researchers in biomedicine and biotechnology and their commercial application. The company was founded by August Krogh, Marie Krogh, Harald Pedersen, Hans Christian Hagedorn, August Kongsted and Thorvald Pedersen in 1922 and is headquartered in Hellerup, Denmark.

Novo Holding A/S provides financial investments and manages the Novo Nordisk Foundation?s assets. It offers seed and venture capital to development stage companies and takes ownership positions in companies within life science and biotechnology. The company was founded on September 8, 1999 and is headquartered in Hellerup, Denmark.

The Scripps Research Institute is a private, non-profit research organizations that performs basic biomedical research in molecular & cellular biology, chemistry, immunology and neuroscience. They receive the majority of its funding from federal agencies such as the National Institutes of Health. The organization also partners with pharmaceutical companies and is affiliated with the Scripps hospital group. The organization was founded in 1955 and is headquartered in La Jolla, California.

Smith & Nephew, Inc. develops and markets medical devices. Its products include television cameras and monitors, endoscopes, arthroscopes, orthopedic hand owered instruments, fiber optic illumination systems, laparoscopes, and surgical instruments. The company was founded on November 27, 1975 and is headquartered in Memphis, TN.

MB Venture Partners LLC (MB Venture Partners) is a venture capital firm founded in 2001 by Gary Stevenson and Joseph R. Hyde III. The firm is headquartered in Memphis, Tennessee.

Shire Pharmaceuticals, Inc. manufactures pharmaceutical products. The company offers solutions for attention deficit & hyperactivity disorder, human genetic therapies, gastrointestinal, and renal diseases. The company was founded in 1986 and is headquartered in Wayne, PA

Novo Ventures (Novo Ventures) is a venture capital operating division of Novo Nordisk Fonden. It engages in investment activities. The firm was established in 1999, and is headquartered in Hellerup, Denmark.

AlloCure, Inc. develops cell therapies for the treatment of kidney diseases. It engages in developing allogeneic mesenchymal stem cell therapy for acute kidney injury. The company was founded in 2008 and is headquartered in Burlington, MA.

Cell Medica Switzerland AG engages in the research, development, production, and distribution of pharmaceutical, biological, medical, and diagnostic products. It provides locally and systemically applied antibody therapeutics under the PENTRA Body platform. The company was founded by Thomas O. Hecht on September 4, 2009 and is headquartered in Schlieren, Switzerland.

PanOptica, Inc. operates as a biopharmaceutical company that provides ophthalmology drugs for treatment of eye diseases. The company was founded by Paul G. Chaney and Martin B. Wax in March 2009 and is headquartered in Bernardsville, NJ.

Imagen Biotech, Inc. develops therapeutics for sight-threatening diseases. The firm specializes in personalized chemotherapy, medicine, high content screening, cell biology and contract research. The company was founded by David R. Guyer and Matthew Feinsod in 2011 and is headquartered in New York, NY.

Better Walk, Inc. operates as a medical device company which designs and develops crutches. The company was founded by Frankie Swindell, Partha Unnava and Andrew Varghese in May 2013 and is headquartered in Atlanta, GA.

Surgilight, Inc. provides surgeons with a comfortable and effective illumination source for deep surgical cavities. It offers a surgical lighting system that enables surgeons with a practical illumination device to focus on minute target areas. The firm connects to overhead surgical light handles, and features a long, flexible shaft that will allow the user to direct the light onto the incision from any desired angle. The company was founded in 2013 by Simren Dhaliwal and John Ratcliffe and is headquartered in Memphis, TN.

Kanyos Bio, Inc. engages in the provision of immune tolerance technology solutions. It develops antigen-specific for treatment of type-1 diabetes and celiac disease. The company was founded by Jeffrey Hubbell, Stephan Kontos, Oscar Buset, Kristen M. Lorentz, and David A. Lowin in 2015 and is headquartered in Cambridge, MA.

Nuvelution Pharma, Inc. provides solutions for R&D companies in the pharmaceutical and biotech industries. The firm leverages its knowledge, experience and relationships in the Pharma and Biotech industries to deploy capital in risk-sharing collaborations with companies where product development can be facilitated by both capital and human resources, making this model an essential tool for pharma and biotech companies to bring products to the market. The company was founded by Sanford S. Zweifach and is headquartered in South San Francisco, CA.

Entasis Therapeutics, Inc. is a clinical-stage biopharmaceutical company, which focuses on the discovey, development, and commercialization of novel antibacterial prodcuts to treat serious infections caused by multi-drug resistant Gram-negative bacteria. Its pipeline includes ETX2514SUL, targeting Acinetobacter baumannii infections; ETX0282CPDP, targeting Enterobacteriaceae infections; a Non-Beta-lactam PBP inhibitor, targeting Gram-negative infections; and zoliflodacin, targeting Neisseria gonorrhoeae. The company was founded by Manoussos Perros in May 2015 and is headquartered in Waltham, MA.

Statera Spine, Inc. operates as a software and technology company, focused on spine imaging informatics and committed to the idea that spine alignment and motion matters. The company is headquartered in Austin, TX.

HighCape Capital LP is a growth equity fund based in New York, NY. HighCape Capital is dedicated to helping innovative life sciences companies transition into successful and thriving organizations. HighCape Capital LP was founded in 2013 by Kevin L. Rakin and he has been the CEO since 2013.

Zeroto510 LLC develops unique programs that enable entrepreneurs with ideas for innovative medical devices.