Jim M. Shapiro

Headquartered in Baltimore, Maryland, Alex. Brown Investment Management LP (ABIM) is a registered investment advisor owned by J. Dorsey Brown and Buppert, Behrens & Owen, Inc.

Hansen Medical, Inc. develops, manufactures, and sells medical robotics designed for positioning, manipulation, and stable control of catheters and catheter-based technologies. It offers Sensei Robotic Catheter System which allows physicians to instinctively navigate flexible catheters with stability and control in interventional procedures within the atria heart chambers. The company was founded by Frederic H. Moll, Daniel T. Wallace, Marvin J. Slepian, and Robert G. Younge on November 18, 2002 and is headquartered in Redwood City, CA.

TriVascular, Inc. develops and manufactures medical devices. It provides devices and procedures for treating abdominal aortic aneurysms and endovascular grafts. The company was founded by Michael V. Chobotov, Robert G. Whirley, and Joseph W. Humphrey in 1998 and is headquartered in Irvine, CA.

SpinalMotion, Inc. is a holding company, which engages in the design, development, and market of cervical artificial discs for use in the spine. The company was founded by James M. Shapiro, Graham Blackbeard and Richard C. Spalding in 2004 and is headquartered in Mountain View, CA.

Baxano, Inc., based in San Jose, California, is focused on developing minimally invasive tools to restore spine function and preserve healthy tissue. Baxano is a well funded, privately held company which was founded in 2005 by Jeffery Bleich, M.D., who had the vision to create flexible tools to provide precision lumbar decompression from the 'inside out.' Baxano's mission is to develop innovative tools that restore spine function, preserve healthy tissue, and enable a better quality of life for the patients it serves. Along with its dedication to advanced technology development, Baxano is focused on providing exceptional value to patients, customers, investors and employees.

Calvert Capital Management Co. (Calvert Capital Management) is a venture capital firm founded in 1982. The firm is headquartered in Waltham, Massachusetts.

eyeonics, Inc. designs, develops, manufactures and sells premium intraocular lenses. Its lenses are implantable devices that replace the natural lens in the human eye, typically after the natural lens has developed cataracts that can significantly impair vision. The firm's products are designed to both replace a cataractous lens and correct a refractive error. The company was founded by Andrew J. Corley and Stuart J. Cumming in 1998 and is headquartered in Aliso Viejo, CA.

TranS1, Inc. designs and develops surgical procedures and equipment for back pain. It is a medical device company focused on designing, developing and marketing products that implement its proprietary approach to treat degenerative conditions of the spine affecting the lower lumbar region. TranS1 currently markets the AxiaLIF family of products for single-level and two-level lumbar fusion and the Vectre and Avatar posterior fixation systems for lumbar fixation supplemental to AxiaLIF fusion. Its primary technology is AxiaLIF, a minimally invasive access and fusion system that enables lumbar fusion to be performed with complete preservation of the annulus and all paraspinal soft tissue structures. The company specializes in bringing innovative spine solutions to market, including AxiaLIF and AxiaLIF 2L+, technologies that allow surgeons to perform lower lumbar fusions that result in high fusion rates and low complication rates. The company is also developing a motion preservation platform to be delivered through this minimally invasive, trans-sacral approach. TranS1 was founded in May 2000 and is headquartered in Wilmington, NC.